Prednisone belongs to the group of glucocorticoid medicines. It is given to the patient to decrease inflammation in the body which can cause diseases like arthritis, asthma, and COPD (chronic obstructive pulmonary diseases). Prednisone when given to the patient, it suppresses the immune system of the body. Also, we observe Prednisone side effects on the human and animal body.
Prednisone is used as an anti-inflammatory and immunosuppressant medicine. This is also given for other conditions like high blood calcium caused due to cancer and also for adrenal insufficiency along with other steroids. It is also given in other diseases which include ulcerative colitis, lupus, psoriasis, and allergic disorders.
Prednisone is considered safe when prescribed in pregnancy and for lactating mother, the dose for prednisone is low as compared with its normal dose.
Prednisone is legal in the United States as a medicine in 1955. This medicine is also available as a generic medicine.
How Prednisone Activates The Inside Liver
After oral administration of this medicine, this medicine has to be converted into prednisolone which is an active state of this medicine. This conversation of prednisone to prednisolone takes place in the liver. After its activation prednisolone binds with glucocorticoid receptors, after which it activates the receptors and starts producing a change in the gene expression.
What Should Be Considered Before Prescribing Prednisone
Prednisone medicine is given in many diseases condition like-
- Breathing difficulty- asthma
- Skin allergies
- Allergic disorders
- Lupus etc
But if a patient is suffering from fungal infection and he/she is taking anti-fungal medicine orally then the patient should avoid taking prednisone medicine during that time. There is no issue if the patient is using tropical fungal medication, but your doctor should have the knowledge that before the patient is starting prednisone medicine, the patient should all medicinal history which includes all medicines patient had taken before.
Prednisone is a steroid. While taking any steroid it lowers down the immune system of the body to fight against diseases. Lower immunity makes the patient easier to catch any kind of sickness which will make the patient much weaker.
So, the advice is given to the patient who is taking prednisone medicine that avoids going to the place where the patient can catch infection easily and stay away from the people who are infected.
While taking prednisone the patient should not receive any kind of live vaccinations. Live vaccination is given to the person so that the body can produce antibodies against the bacteria or virus. This boosts up the immune system of the normal healthy person.
If you are taking prednisone after which if you have symptoms like
- Severe pain in the upper chest
- Difficulty in breathing
- Blood in stool
- Severe depression
- Change in the personality or behavior
- Difficulty in vision
Stop taking the prednisone medicine and don’t delay in calling your doctor.
Also, read – Prednisone and alcohol: Can I have them together?
How Can I Take My Prednisone Medicine Dosage?
Prednisone medicine comes in three forms- tablets, liquid form (solution), and concentrated liquid. This medicine is taken one to four times a day or one dose for a whole day with food. It all depends upon your doctor that how much dosage your doctor will start; also depend upon the patient medical condition and how the patient is responding after giving the prednisone medicine.
If your doctor has prescribed you prednisone medicine than you should follow the prescription carefully and in case if you are not able to understand anything then don’t hesitate to ask your doctor or pharmacist before taking medicine.
If the doctor has prescribed you prednisone in a concentrated form than follow the instructions labeled in the cap that how much medicine should be taken measured by the special marker in the dropper for your dose. Even you can have this solution with juices, any flavored liquids or any soft foods.
Tablets are only swallowed don’t chew or crush. Do not stop your prednisone medicine suddenly and you should follow the instruction given to you by your doctor before you are tapering your dose.
Store prednisone medicine at room temperature away from moisture and heat. You must follow the dose advised by the doctor.
When My Doctor Can Change The Dosage Of Prednisone Medicine?
Your doctor can change your dose of prednisone medicine during the ongoing treatment so that you are taking the lowest dose of the steroid which will work for your illness.
Your doctor can even change the dose of prednisone medicine if you are having any kind of other illnesses like unusual stress on your body for the normal function of the body, any surgery, any infection or severe breathing problem. Call your doctor immediately if your symptoms are getting worsens or improved or any kind of sickness during ongoing treatment.
Medical History Your Doctor Must Know Before Starting Prednisone
It is very important for the doctor to know the past medical history of the patient before the doctor starts with prednisone medicine. As this medicine lowers the immune system of the body, the patient will be more prone to catch any infection which can even worsen the health of the patient.
The following medical history should be told to the doctor before starting prednisone medicine: –
- Heart diseases
- High blood pressure,
- Low levels of potassium in the blood;
- Thyroid disorders
- Diabetes mellitus
- Malaria, dengue
- Any illness which produces diarrhea
- Liver diseases
- Kidney diseases
- Herpes infection of the eyes
- Stomach ulcers
- Ulcerative colitis, Crohn’s disease (Irritable bowel diseases)
- Any history of stomach bleeding;
- Muscle disorders like myasthenia gravis
- Mental illness.
If you are taking prednisone for the long term, then your bone can suffer from osteoporosis.
It is mostly seen in patients who are smokers, who do not take enough calcium and vitamin D in their diet, who do not go for regular exercise or who have a family history of osteoporosis. So, if you have any bone pain during prednisone treatment than tell your doctor about it.
Prednisone Medicine in Pregnancy and Lactation
Prednisone medicine if taken during the first trimester of the pregnancy than there is increased chances of low birth weight or increased chances of having any birth defects. So, if you are taking prednisone medicine and if you are planning to conceive than tell your doctor before your plan so that your doctor can change your medicine before you become pregnant.
In studies, it has shown that there are no side effects of prednisone medicine taken during pregnancy while in few studies it has shown the low birth weight or birth defects. So, consult your doctor first to get information about it and don’t hesitate to ask anything related to it.
While in lactation, prednisone medicine can pass through breast milk and can produce harm to the nursing baby. For this also tell your doctor if you are taking medicine and feeding the baby.
Prednisone medicines can even affect the normal growth of the child. So, if any child is taking prednisone medicine and growth is not proper to tell your doctor for this also.
Dietary Management for a Patient Taking Prednisone Medicine
For the patient who is under prednisone treatment should take-
- Low salt diet
- High potassium diet
- High calcium diet
- Can take potassium or calcium supplements
- It can eat grapefruit and can drink grapefruit juice.
What If I Miss My Prednisone Medicine Dosage?
Tell your doctor that if you missed a dose of your medicine. Your doctor will advise you to take medicine when you remember about it but it is already the time to take the next dose then don’t take that skip dose. Remember not to take extra medicine to cover the missed dose.
What If I Take An Overdose Of My Prednisone Medicine?
If you ever have an overdose of prednisone medicine than calling the poison control helpline.
Overdosing prednisone medicine not produce a threatening medical condition. But if a patient is taking a high dose of prednisone medicine for a longer time than the following symptoms can be seen: –
- Change in shape or any location of the body due to increased fat
- Acnes on skin
- Increased facial hairs
- Thinning of the skin
- Easy bruising
- Menstrual irregularities
- Loss of interest in intercourse.
Side Effects of Prednisone Medicine
The following side effects of taking prednisone medicine. If any of the symptoms get severe or do not stop then tell your doctor about it.
Common Side Effects of Prednisone Medicine
- Slow healing of cuts and bruises in the body
- Increased hair growth in the body
- Increased fat amount in the body at different localities
- Extreme weakness
- Weak muscles
- Irregular or absent menstruation
- Loss of sexual desire
- Heartburn (acidity)
- Increase sweating
- Headache and dizziness
- Difficulty in sleeping
- Inappropriate happiness
- Extreme changes in mood
- Changes in personality
- Bulging of eyes
- Acne on the body
- Thin, fragile skin of the body
- Red or purple color patches or lines under the skin
Serious Side Effects of Prednisone Medicine
Along with this, there are some serious side effects that are seen after taking prednisone medicine which should be told to the doctor immediately.
- Sudden weight gain
- Shortness of breath especially occurring during the night
- Dry hacking cough
- Swelling or pain in the stomach
- Swelling of the body especially eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
- Difficulty breathing and swallowing
- Rash and hives with severe itching
- Difficulty in vision with eye pain, redness, or tearing pain
- Sore throat and fever with chills, cough, or other signs of infection
- Loss of contact with reality
- Confusion state
- Twitching or tightening of muscles
- Shaking of the hands that you cannot control (involuntary movements)
- Numbness with burning, or tingling in the face, arms, legs, feet, or hands
- Stomach problem (difficulty indigestion)
- Vomiting or nausea
- Irregular heartbeat
Your doctor will advise you to have certain tests like allergic test or tuberculosis test. Tell the technician that you are under prednisone treatment for which you are conducting this test.
While taking an arrangement to the specialist remember to keep all your restorative archives that incorporate every one of the tests and past therapeutic records or some other enhancements in the event that you are bringing, at that point rundown ought to be available in your medicinal document.
Additionally, give insight regarding other ailments while taking prednisone drug. Keep in mind that prednisone is a steroid that brings down your insusceptible framework so the specialist will encourage you to remain away from diseases. Furthermore, the most significant is ward off the drug from the scope of your children’s
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